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A 68-year-old woman with nodular bronchiectasis presents with persistent productive cough, intermittent regurgitation and recurrent ‘chest infections’ despite 12 months of once-daily proton pump inhibitor (PPI) therapy. Her clinician has doubled the PPI dose and is considering long-term azithromycin. Sputum has not been sent for mycobacterial culture in over a year. She has lost 3 kg, at times […]

Christopher Butler, ERS 2020 – Antiviral Therapy for Influenza

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Published Online: Sep 14th 2020

We were delighted to speak with Prof. Christopher Butler (University of Oxford, Oxford, UK) about antiviral therapies for influenza and, in particular, the findings from the ALIC4E trial.

Questions
1. What are the current recommendations for the use of antiviral therapy for the treatment of influenza? (0:07)
2. Why is oseltamivir not more widely used in the treatment of influenza? (1:00)
3. Could you tell us a little about the ALIC4E clinical trial design and its findings in terms of who is most likely to benefit? (2:32)
4. What other studies are ongoing/are planned? (5:18)

Speaker disclosure: Christopher Butler is the principal investigator of the ALIC4E clinical trial.

Support: Interview and filming supported by Touch Medical Media.

Filmed in coverage of the ERS International Congress 2020.

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