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2025 PHPN Symposium recap: Innovations in pulmonary hypertension diagnosis and care

Jean M Elwing
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PHPN 2025
Published Online: Oct 7th 2025

2025 PHPN Symposium recap: Innovations in pulmonary hypertension diagnosis and care

The Pulmonary Hypertension Professional Network (PHPN) Symposium, hosted by the Pulmonary Hypertension Association, is a leading event for healthcare professionals specialising in pulmonary hypertension (PH). It brings together experts to share the latest research, clinical practices, and treatment advances, fostering collaboration and innovation to improve patient outcomes and care for this complex condition.

In this Q&A, Dr Jean Elwing (UC Medical Center, Cincinnati, OH, USA) highlights key takeaways from the 2025 Symposium, including new right heart echocardiography guidelines, health equity challenges in methamphetamine-associated pulmonary arterial hypertension (PAH), and promising therapies like sotatercept. Dr Elwing also reflects on the importance of early detection, personalized medicine, and multidisciplinary teamwork to address ongoing challenges and drive progress toward better outcomes and, ultimately, a cure.

Q. Were there any key presentations, sessions, or posters that stood out for you?

Several sessions were particularly impactful. “PHocus on the Right Heart: Clinical Application of the New 2025 Right Heart Echocardiography Guidelines,” led by Professor Anjali Vaidya, MD from Temple University, provided practical guidance on implementing the new guidelines. Professor Vaidya emphasized standardized, multiparametric RV assessment and the integration of advanced echo techniques, highlighting their impact on clinical decision-making in pulmonary hypertension.

Another standout was “Exploring the Role of Race and Ethnicity in Methamphetamine Use Patterns in PAH,” led by Dr Raquel Lyn, MD. This session addressed a critical area of health equity, focusing on the rise in methamphetamine use among underrepresented minorities and its contribution to methamphetamine-associated PAH (Meth-APAH). Dr Lyn highlighted the lack of standardized substance use screening in PAH patients and called for more research and practical strategies to address disparities and optimize care.

Q. What was the most impactful takeaway for pulmonologists from this year’s PHPN Symposium?

There was an overwhelming sense of positive energy and optimism for the future of PAH, with a strong commitment to advancing patient care. Exciting progress is being made with new medications and therapies, offering hope for improved outcomes and quality of life. The importance of teamwork and multidisciplinary collaboration was emphasized throughout the conference, driving innovation and pushing the field forward.

Q. Did you learn about any new treatments or diagnostic approaches that could change PH care?

Yes, the session “Spotlight on a Treatment Option for Pulmonary Arterial Hypertension (PAH)” featured Corinne Young, FNP, FCCP, who highlighted sotatercept as a novel, disease-modifying option for PAH. Supported by robust phase 2/3 data, sotatercept demonstrated significant improvements in exercise capacity, hemodynamics, and clinical outcomes, with a favourable safety profile. These results support sotatercept as an important addition to PAH care.

Q. What challenges in managing PH stood out during the sessions?

Despite advances in therapies and imaging, the challenge of continued progressive disease remains significant. Delays in diagnosis persist, often resulting in patients presenting at more advanced stages, and there is still no definitive cure for PAH. These challenges underscore the urgent need for continued research, earlier detection strategies, and innovative treatment approaches. The conference emphasized that while progress is being made, much more work is needed to improve outcomes and close gaps in care.

Q. Which areas of PH research or care need the most attention moving forward?

A critical area needing attention is the exploration of novel therapeutic pathways that could promote disease regression and, ultimately, a cure. Advancing research into these mechanisms is essential for moving beyond symptom management. There is also a growing need for personalized medicine approaches to tailor therapies to individual patient profiles. Continued support and resources for multidisciplinary teams are vital, as collaborative care models drive innovation and ensure comprehensive management of this complex disease.

Q. What were your personal highlights from this year’s PHPN Symposium?

One of my personal highlights was the “Pulmonary Hypertension JEOPARDY!” session. This prime-time gameshow was a standout, combining education and fun with excellent engagement. Led by Dr Robert Schilz, DO, it covered essential PAH topics in an interactive format that kept the audience involved.

One of the most impressive aspects of the conference was the outstanding attendance and high level of audience engagement. The large number of presented abstracts reflected the vibrant research activity in the field. The lightning rounds, in particular, provided an excellent platform for younger providers to showcase their work and research, fostering knowledge sharing and encouraging the next generation of clinicians and investigators to actively contribute to the advancement of pulmonary hypertension care and science.

Resources

  • Pulmonary Hypertension Association. Attend PHA’s PHPN Symposium in Seattle. Available at: https://symposium.phassociation.org/home.cfm (accessed 29 September 2025).
  • Cormican DS. 2025 ASE Guidelines on Echocardiographic Evaluation of the Right Heart with Focus on Pulmonary Hypertension: A Welcome and Necessary Update. J Cardiothorac Vasc Anesth. 2025:In Press.

Further content in pulmonary hypertension.

Editor: Victoria Smith, Senior Content Editor.

Cite: 2025 PHPN Symposium recap: Innovations in pulmonary hypertension diagnosis and care. touchRESPIRATORY. 7 October 2025.

Disclosures: This short article was prepared by touchRESPIRATORY in collaboration with Jean Elwing, it is not affiliated with the Pulmonary Hypertension Professional Network (PHPN) Symposium. Views expressed are the speaker’s own and do not necessarily reflect the views of Touch Medical Media. touchRESPIRATORY utilize AI as an editorial tool (ChatGPT (GPT-4o) [Large language model]. https://chat.openai.com/chat.) No fees or funding were associated with its publication.

Jean Elwing discloses receiving grant/research support from: Acceleron/Merck, Gossamer Bio, Inhibikase, Lung LLC, Novartis, NS Pharma, Pharmosa/Liquidia, Pulmovant, United Therapeutics; serving on advisory boards for: Aerovate, Gossamer Bio, Insmed, Janssen/Actelion/Johnson & Johnson, Liquida, Merck, Pulmovant, United Therapeutics; and receiving honoraria/honorarium from: Janssen/Actelion/Johnson & Johnson.


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2025 PHPN Symposium Recap: Innovations in Pulmonary Hypertension Diagnosis and Care


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