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Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

Peter Dicpinigaitis, ERS 2021: Gefapixant for Chronic Cough

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Published Online: Sep 22nd 2021

It was a pleasure to meet with Professor Peter Dicpinigaitis (Albert Einstein College of Medicine and Montefiore Cough Center, NY, USA) to discuss the findings from the COUGH-1 and COUGH-2 studies, investigating gefapixant for the treatment of patients with chronic cough.

The abstract ‘Patient-reported chronic cough severity over 52 weeks in two phase 3 trials of gefapixant.’ (Presentation ID 1588) was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. How were patient reported cough severity outcomes measured in the COUGH-1 and COUGH-2 studies? (0:15)
  2. What were the aims, design and inclusion criteria of the COUGH-1 and COUGH-2 studies? (0:48)
  3. What were the findings from the main study periods? (1:32)
  4. Were these findings maintained in the extension periods up to 52 weeks? (1:56)

Disclosures: Peter Dicpinigaitis is a consultant to Merck, who sponsored the research discussed in the interview.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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