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Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

Michael Blaiss, AAAAI 2022: An Analysis of Gefapixant in Chronic Cough

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Published Online: Mar 14th 2022

touchRESPIRATORY caught up with Dr. Michael S. Blaiss (Medical College of Georgia, Augusta University, Augusta, GA, USA) to discuss his analysis of phase 3 trials of gefapixant in chronic cough.

The abstract ‘Comparisons Of Baseline Characteristics And Treatment Efficacy In Individuals With Refractory Or Unexplained Chronic Cough Enrolled In Phase 3 Trials Of Gefapixant‘ was presented at AAAAI 2022, 25-28 February.

Questions

  1. What have the COUGH-1 and COUGH-2 studies taught us about the efficacy and safety of gefapixant in patients with RCC or UCC? (0:20)
  2. What were the aims of the current comparison of baseline characteristics and treatment efficacy in patients in these two studies? (1:49)
  3. What questions remain unanswered? (3:22)

Disclosures: Michael Blaiss discloses consulting for Merck and Bellus, serving on advisory boards for Merck and Bellus, and participating in Speaker’s Bureaus for Merck.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Victoria Jones.

Filmed in coverage of the AAAAI meeting 2022

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