Paediatric Respiratory Medicine

Dupilumab is indicated as an add-on maintenance treatment in children aged 6 years and older with asthma, and demonstrated clinical efficacy in the pivotal VOYAGE study (NCT0294895). We caught up with Dr Theresa W Guilbert (Cincinnati Children’s Hospital & Medical Center; University of Cincinnati, Cincinnati, OH, USA) to discuss the main findings from a post-hoc […]

touchRESPIRATORY were delighted to speak with Dr Theresa W Guilbert (Cincinnati Children’s Hospital & Medical Center; University of Cincinnati, Cincinnati, OH, USA) about the health and economic burden of asthma exacerbations in children, and the limitations of current therapeutic options for children with asthma. The abstract ‘Impact Of Exacerbation History On Dupilumab Efficacy In Children […]

The InPedILD trial was a phase 3, double-blind placebo-controlled trial investigating nintedanib in children and adolescents with fibrosing interstitial lung diseases (ClinicalTrials.gov: NCT04093024). We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) to discuss the aims, design, eligibility criteria and findings from the phase 3 study. […]

Nintedanib is an inhibitor of tyrosine kinases involved in the progression of pulmonary fibrosis and blocks the signalling pathways involved in fibrotic processes. We were delighted to speak to Dr. Robin Deterding (University of Colorado; Children’s Hospital Colorado, Aurora, CO, USA) around the incidence, prognosis and unmet needs in the treatment of childhood interstitial lung […]

Editorial board member and new Chair Elect of the Paediatric Respiratory Physiology and Sleep Section of the ERS Paediatric Assembly Refika Ersu (Marmara University, Istanbul, Turkey) chats to us about unmet needs and exciting advances in respiratory and sleep physiology in children. Questions 1. What are the major unmet needs in paediatric sleep medicine? (0:12) […]

Editorial board member Fabio Midulla (Sapienza University, Rome, Italy) chats to us about acute viral bronchiolitis, including risk factors, challenges managing the condition, risks and recent advances. Questions 1. What are the major risk factors for acute viral bronchiolitis? (0:12) 2. What are the challenges in the management of acute viral bronchiolitis? (1:02) 3. What […]