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A 68-year-old woman with nodular bronchiectasis presents with persistent productive cough, intermittent regurgitation and recurrent ‘chest infections’ despite 12 months of once-daily proton pump inhibitor (PPI) therapy. Her clinician has doubled the PPI dose and is considering long-term azithromycin. Sputum has not been sent for mycobacterial culture in over a year. She has lost 3 kg, at times […]

Stella Lee, AAAAI 2021: Current Therapies for the Treatment of Chronic Rhinosinusitis with Nasal Polyps

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Published Online: Mar 29th 2021

We were delighted to talk to Dr Stella Lee (University of Pittsburgh, Pittsburgh, PA, US) around the current and future treatment options for chronic rhinosinusitis with nasal polyps.

Questions

  1. What is the impact of chronic rhinosinusitis with nasal polyps on quality of life, and what are the limitations of current therapies? (0:18)
  2. What biologics are currently available in this treatment setting? (2:43)
  3. What role are biologics likely to play in the future treatment of chronic rhinosinusitis with nasal polyps? (4:29)

Disclosures: Clinical trial funding and participation on advisory boards for: AstraZeneca, Genentech, GlaxoSmithKline, Sanofi Regeneron.

Support: Interview and filming supported by Touch Medical Media.

Filmed as a highlight of AAAAI 2021 (Virtual).

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