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Kate Clair Cruden Hughes, Amy Hai Yan Chan

Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

EUROPEAN RESPIRATORY & PULMONARY DISEASES – VOLUME 2 ISSUE 2 – AUTUMN 2016

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Welcome to the latest edition of European Respiratory & Pulmonary Diseases, which features a wide range of topical reviews and editorials. This issue begins with a discussion by Griesenbach and Alton of gene therapy in cystic fibrosis, a subject that has recently experienced a resurgence in interest within the medical community. Pulmonary arterial hypertension (PAH) […]

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Editorials

Cystic fibrosis (CF) is caused by mutations in a single gene; treatment burden is high and life expectancy is significantly shortened (median age of survival in the UK is ~40 years). Although CF is a multi-organ disease, chronic lung infection and inflammation are the biggest causes of morbidity and mortality in the developed world. Identification […]

Pulmonary arterial hypertension (PAH) is a rare, deadly and incurable condition.1 With a five-year survival rate below 60%, the outcome of this disease is not any better than that of many cancers.1,2 However, numerous treatment options are currently available: more than 20 randomised controlled trials (RCTs) have been conducted over the past 10 years, allowing […]

Breathing problems during sleep commonly occur in children. Obstructive sleep apnoea (OSA) is the most common breathing-related problem that occurs during sleep and snoring is the main symptom. Habitual snoring, which is defined as snoring for more than three days a week, is seen in 7.45% of children.1 OSA is defined as recurrent events of […]

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Review

Nontuberculous mycobacteria (NTM) are a diverse group of bacteria with a wide spectrum of virulence.1 They are a microaerobic, non-motile organisms that have a lipid-rich, hydrophobic cell wall that is substantially thicker compared with most other bacteria.2 NTM are associated with biofilm formation, which contributes to disinfectant- and antibiotic-resistance.3–5 Many of these organisms are also […]

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Case Report

Primary lung carcinoma spreading to pulmonary vessels and presenting as a thromboembolic disease is quite rare and only few individual cases have been reported in the English literature.1-3 The prognostic significance of pulmonary vessel invasion by lung carcinoma is unclear and the treatment is challenging. We aim to describe an unusual case of sarcomatoid carcinoma […]

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European Respiratory & Pulmonary Diseases is a peer-reviewed, free-to-access, annual journal comprising review articles, case reports, practice guides, theoretical discussions, and original research. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in the field of respiratory.

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