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Tuberculosis (TB) has risen once again, as of 2023, to return to being the world’s deadliest infectious disease. TB causes around one million deaths annually, leaving devastating impacts on patients and their communities.1 Historically, TB has been treated in separate TB clinics worldwide that are independent under public health systems, generally isolated from standard primary-care clinics. In […]

Alan Kirk, ERS 2021: The TRANSFORM Study – A 24-month Follow-up

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Published Online: Sep 20th 2021

We were delighted to catch up with Mr Alan Kirk (Golden Jubilee National Hospital, West Dunbartonshire, Scotland, UK) to discuss the 24-month follow-up to the TRANSFORM study, investigating endobronchial valve treatment for patients with severe heterogeneous emphysema.

The abstract ‘Durability of Zephyr Valve treatment: 24-month follow-up in the TRANSFORM Study.‘ (Presentation ID: 1201) was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. Can you briefly outline how the Zephyr Valve works and who the target population are? (0:15)
  2. What benefits were demonstrated with the Zephyr Valve over 6 months during the TRANSFORM study? (2:41)
  3. Were treatment benefits maintained over the 24-month follow-up to the TRANSFORM study? (3:57)
  4. What are the implications of these results for patients with severe heterogeneous emphysema? (5:00)
  5. What unmet needs still remain for patients with emphysema? (6:26)

Disclosures: Alan Kirk discloses receiving research funding from Pulmonx for TRANSFORM and CONVERT studies.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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