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Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

Molla Imaduddin Ahmed, ERS 2021: Tezacaftor/Ivacaftor Effect on Exercise Capacity in Adolescents with Cystic Fibrosis

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Published Online: Sep 30th 2021

It was a pleasure to speak with Dr Molla Imaduddin Ahmed (Leicester Childrens’ Hospital, Leicester, UK) around his abstract on ‘The impact of Symkevi (Tezacaftor/Ivacaftor) on exercise capacity in adolescents with CF.‘, which was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. How useful is exercise capacity as a clinical endpoint for cystic fibrosis (CF)? (0:20)
  2. What were the aims and design of your recent study of Tezacaftor/Ivacaftor on exercise capacity in adolescents with CF? (1:50)
  3. What were the findings of this study? (2:52)
  4. What are the implications of these findings in terms of future clinical trial design? (4:33)

Disclosures: Molla Imaduddin Ahmed has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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