It was delightful to speak to Editorial Board member Peter J Barnes at ERS 2019 in Madrid about chronic obstructive pulmonary disease as a disease of accelerated lung ageing.
Questions
1. What are the main similarities between ageing lungs and the lungs of chronic obstructive pulmonary disease (COPD) patients? (0:07)
2. What have these similarities taught us about the pathogenesis of COPD? (0:34)
3. Which ageing-related molecular pathways are the most promising therapeutic targets for COPD? (1:02)
4. How can we use these ageing parameters to predict which patients are most likely to develop COPD? (1:51)
5. What other chronic lung diseases show signs of accelerated lung ageing? (2:23)
Speaker disclosures: Peter J Barnes has received research funding from AstraZeneca and Boehringer Ingelheim, advisory board/consultancy fees for AstraZeneca, Boehringer Ingelheim, Novartis, Pieris. He has been a speaker for AstraZeneca, Boehringer Ingelheim, Novartis, Teva.
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Filmed at the European Respiratory Society (ERS) International Congress 2019, Madrid, Spain.