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Tuberculosis (TB) has risen once again, as of 2023, to return to being the world’s deadliest infectious disease. TB causes around one million deaths annually, leaving devastating impacts on patients and their communities.1 Historically, TB has been treated in separate TB clinics worldwide that are independent under public health systems, generally isolated from standard primary-care clinics. In […]

Frédéric de Blay, EAACI 2021: Anti-Fel D 1 Monoclonal Antibodies Reduce the Rate of Early Asthma Responses

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Published Online: Sep 7th 2021

touchRESPIRATORY joins Professor Frédéric de Blay (University Hospital of Strasbourg, Strasbourg, France) at EAACI 2021 to discuss the results of a phase 2, randomised, double-blind, placebo-controlled study of anti-Fel d 1 monoclonal antibodies in reducing the rate of early asthma responses, chest symptoms and rescue medication use in cat-allergic subjects with mild asthma for up to 3 months following a controlled cat allergen challenge.

NCT03838731

Questions
1. Could you give us a brief overview of the health burden of cat allergy? (00:29-01:57)
2. What are anti-Fel d 1 monoclonal antibodies and what is the rationale for use in combating cat allergy? (01:57 -02:43)
3. What were the aims and design of the Phase 2 study? (02:43-04:00)
4. What were the efficacy and safety findings of the study? (04:00-05:00)
5. What will be the next step in the clinical development of anti-Fel d 1 monoclonal antibodies? (05:00-06:04)

Disclosures: Professor Frédéric de Blay has no financial or non-financial conflicts of interest to declare in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Sophie Nickelson.

Filmed in coverage of the 2021 EAACI Annual Meeting.

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