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Kate Clair Cruden Hughes, Amy Hai Yan Chan

Asthma affects nearly 300 million people worldwide.1 Despite a notable decline in age-standardized prevalence, mortality and disability-adjusted life years over the past three decades, the burden of asthma remains high in many countries including low-middle-income countries.2 Climate change is also predicted to significantly impact asthma and other respiratory-related conditions, as rising global temperatures lead to longer pollen […]

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The nasal airway serves as the primary entry point of air and oxygen into the body. It serves critical functions, such as providing a physical barrier against external irritants and pathogens and warming and humidifying incoming air.1 Consequently, disorders of ...

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Meredith K Greer, Saiprakash B Venkateshiah

Obesity hypoventilation syndrome (OHS) is defined as daytime hypercapnia (awake resting PaCO2 of ≥45 mmHg) in the setting of obesity (body mass index [BMI] ≥30 kg/m2). Most, if not all, patients have some sleep disordered breathing in the form of obstructive ...

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Chronic obstructive pulmonary disease (COPD) imposes a substantial health and economic burden worldwide and is a major cause of death.1 Clinical features of advanced COPD include severe airway obstruction and lung hyperinflation that can lead to chronic respiratory failure, which ...

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Primary lung carcinoma spreading to pulmonary vessels and presenting as a thromboembolic disease is quite rare and only few individual cases have been reported in the English literature.1-3 The prognostic significance of pulmonary vessel invasion by lung carcinoma is ...

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Adaptive servo-ventilation (ASV) is a non-invasive ventilatory therapy that provides variable inspiratory positive airway pressure (IPAP) to support inspiration when breathing amplitude is reduced, ensures sufficient respiration when respiratory effort is absent and provides fixed or variable end-expiratory PAP (EPAP) ...

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