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A 68-year-old woman with nodular bronchiectasis presents with persistent productive cough, intermittent regurgitation and recurrent ‘chest infections’ despite 12 months of once-daily proton pump inhibitor (PPI) therapy. Her clinician has doubled the PPI dose and is considering long-term azithromycin. Sputum has not been sent for mycobacterial culture in over a year. She has lost 3 kg, at times […]

Donald Mahler, CHEST 2021: Precision Medicine in COPD

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Published Online: Oct 25th 2021

We were delighted to speak with Prof. Donald Mahler (Geisel School of Medicine, Dartmouth, NH, USA) to explore his presentation ‘Precision Medicine in COPD’, which was presented at CHEST 2021, 17-20 October 2021.

Questions

  1. What is the limitation of traditional approaches to the treatment of COPD? (0:26)
  2. What are the major challenges of moving to precision medicine in COPD? (1:46)
  3. What are the most promising emerging predictive biomarkers in COPD? (2:53)
  4. What other clinical features can guide therapeutic choice in COPD? (5:08)
  5. What is the current status of precision medicine in COPD and how do you envisage this field developing in the coming years? (6:22)

Disclosures: Donald Mahler has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of CHEST 2021 (Virtual).

For further information please visit Prof. Mahler’s website here: https://www.donaldmahler.com.

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