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Tuberculosis (TB) has risen once again, as of 2023, to return to being the world’s deadliest infectious disease. TB causes around one million deaths annually, leaving devastating impacts on patients and their communities.1 Historically, TB has been treated in separate TB clinics worldwide that are independent under public health systems, generally isolated from standard primary-care clinics. In […]

Molla Imaduddin Ahmed, ERS 2021: Tezacaftor/Ivacaftor Effect on Exercise Capacity in Adolescents with Cystic Fibrosis

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Published Online: Sep 30th 2021

It was a pleasure to speak with Dr Molla Imaduddin Ahmed (Leicester Childrens’ Hospital, Leicester, UK) around his abstract on ‘The impact of Symkevi (Tezacaftor/Ivacaftor) on exercise capacity in adolescents with CF.‘, which was presented at ERS International Congress 2021, 5-8 September 2021.

Questions

  1. How useful is exercise capacity as a clinical endpoint for cystic fibrosis (CF)? (0:20)
  2. What were the aims and design of your recent study of Tezacaftor/Ivacaftor on exercise capacity in adolescents with CF? (1:50)
  3. What were the findings of this study? (2:52)
  4. What are the implications of these findings in terms of future clinical trial design? (4:33)

Disclosures: Molla Imaduddin Ahmed has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Victoria Jones.

Filmed as a highlight of ERS 2021 (Virtual).

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