{"id":68327,"date":"2024-10-01T10:25:33","date_gmt":"2024-10-01T09:25:33","guid":{"rendered":"https:\/\/touchrespiratory.com\/?post_type=insight&p=68327"},"modified":"2024-10-01T10:25:33","modified_gmt":"2024-10-01T09:25:33","slug":"european-respiratory-society-publish-new-statement-on-preschool-wheezing-disorders","status":"publish","type":"insight","link":"https:\/\/touchrespiratory.com\/insight\/european-respiratory-society-publish-new-statement-on-preschool-wheezing-disorders\/","title":{"rendered":"European Respiratory Society publish new statement on preschool wheezing disorders"},"content":{"rendered":"
Preschool wheezing is a common and heterogeneous condition, characterized by various clinical presentations and triggers, ranging from viral infections to multiple environmental and genetic factors. The task force reports published previously in <\/span>2008<\/span> <\/span><\/a>and <\/span>2014<\/span> <\/span><\/a>were, based largely on episodic (viral) wheezing and multiple-trigger wheezing, which has since been found to be inadequate for predicting responses to treatment or understanding underlying airway pathology.\u00a0<\/span><\/p>\n The task force proposed revised definitions for preschool wheezing disorders, identified knowledge gaps, and prioritized future research directions to improve clinical management. Their focus was on enhancing symptom control and preventing wheezing episodes, rather than predicting the progression to asthma. They established three overarching aims to guide their efforts:<\/span><\/p>\n The ERS statement outlines several key areas for future research. First, there is a strong need to better understand the mechanisms driving preschool wheezing, particularly the role of infections and inflammation. Identifying biomarkers that can reliably predict treatment outcomes in non-allergic wheezing cases is a high priority, as current tools are mostly focused on allergic phenotypes.<\/span><\/p>\n Second, the statement stresses the need for well-designed clinical trials that include both objective outcomes, such as lung function and biomarkers, and caregiver-reported outcomes. A key area of interest is whether early intervention in preschool wheezing can modify the disease trajectory and prevent the development of asthma later in life.<\/span><\/p>\n Finally, the task force calls for clearer definitions of severe or difficult-to-treat preschool wheezing, which would help guide when to refer children to specialist care.<\/span><\/p>\nA new European Respiratory Society (ERS) statement<\/a><\/span> on preschool wheezing disorders represents a significant update in the approach to diagnosing and managing this complex condition in young children.<\/span><\/p>\n
1. Summarise current definitions for preschool wheezing in clinical guidelines and definitions used in preschool wheezing research studies<\/h1>\n
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2. Identify current evidence defining the physiology, pathology and mechanisms underpinning preschool wheezing<\/h1>\n
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3. Important outcomes for patients, caregivers and clinicians following diagnosis and\/or management of preschool wheezing<\/h1>\n
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